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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:prolactin signaling pathway
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Accession:GO:0038161 term browser browse the term
Definition:The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PRL signaling pathway;   prolactin-mediated signaling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi

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prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631 		JBrowse link
G PRLR prolactin receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 4:33,933,601...34,108,653
Ensembl chr 4:33,949,935...34,108,619 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in ISO (PMID:23619365) BHF-UCL PMID:23619365 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
positive regulation of prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor acts_upstream_of_or_within ISO (PMID:23071095) MGI PMID:23071095 NCBI chr23:75,219,847...75,302,641
Ensembl chr23:75,219,873...75,297,114 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    cellular process 15887
      signal transduction 5543
        hormone-mediated signaling pathway 189
          prolactin signaling pathway 4
            negative regulation of prolactin signaling pathway 0
            positive regulation of prolactin signaling pathway 1
            regulation of prolactin signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 16925
    response to stimulus 8690
      cellular response to stimulus 7178
        cellular response to chemical stimulus 3024
          cellular response to organic substance 2253
            cellular response to hormone stimulus 771
              hormone-mediated signaling pathway 189
                prolactin signaling pathway 4
                  negative regulation of prolactin signaling pathway 0
                  positive regulation of prolactin signaling pathway 1
                  regulation of prolactin signaling pathway + 1
paths to the root